Role of CRO’s in Phase I Studies

Medical researches include clinical trials as well as various medical studies. A prominent one is know as the Phase I studies and trials that centers around a new treatment or drugs used in humans. The main objective of these studies is to learn and study about the best dosing schedule. The study includes objectives such as the manner is which a drug is given, the amount of the drug and the frequency at which the drug is given. Medical researchers concentrate on the learning about the drug and its toxic or any other harmful effects.


Eminent Clinical Research Organizations in India conducts Phase I studies, that are in turn supported by their experience in Clinical trials. These organizations are equipped with advanced state-of-the-art infrastructure and have volunteers that assist in the studies. Some of the component includes the following:-


* First-in-human

* Single Ascending Dose studies

* Multiple Ascending Dose studies

* New Chemical Entities

* Dose Escalating studies

* Capabilities


In addition to the above mentioned services, the CRO’s also provide Phase I Studies for instance First –in-Man for the New Chemical Entities (NCE’s) and also the New Biological Entities (NBEs).  In addition to that, there are a diverse range of medical pharmacology studies that comprise Drug Inspection studies, Proof of Mechanism & Proof of Concept, Food Effect, TQTc studies, Pharmacokinetic / Pharmacodynamic studies as well as explanatory studies for multiple biomarkers and Special Popular studies.


Importance of Infrastructure in Phase I Studies


Infrastructure plays an important part in Phase I studies and various other researches that are associated with it.  Most CRO’s have well equipped bed units that are managed efficiently by a team of expert professionals having the required medical experience and equipped with state-of-the-art clinical devices. This apart there are also well trained nursing staffs and experienced physicians. These staffs have hands on experience in carrying on First-in-human and other clinical Pharmacology studies. In India, there are eminent CRO’s in the southern part of the country where Phase i Studies are conducted.


These CRO’s have vast experience in conducting medical researches and trials in patient and special populations. Their service portfolio covers Phase I to III studies for various global biotechnology and pharmaceutical companies. They also help in end-to-end Clinical trials.  This apart some of the other services that they provide include Bio Studies, Regulatory Compliance Services, Biometrics, Medical Writing and Bioanalytical Research and have an impressive track record and client feedback.


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Social Analytics to Better your Business

Many companies have become aware of the importance of “listening” and customer engagement, and are looking at capitalizing on social media and social analytics. There’s no doubt that social media is hot and growing at a phenomenal rate. Smart companies are taking note and analyzing the numerous conversations available online, integrating the information gained into their overall go-to-market and business strategy. A recent Forrester Research predicts Interactive marketing spending in the US will more than triple over the next five years, reaching $61 billion by 2012 and spending on social media alone will grow to $6.9 billion as marketers understand how to use and measure this channel.

Social only works if you know how to measure the results and one of the core ways to make those measurements is through analytics. Social media analytics offers an entirely new standard for calculate interactive marketing by integrating, analyzing and enabling organizations to act on intelligence gained by expanding their reach, increasing retention, and ultimately, driving more revenue. With effective Social Analytics, a business can bring you closer to your customer, uncover untapped markets, and provide insight into your competitors. So it becomes imperative to determine which social media monitoring solution is right for the business.

Having a firm understanding of the key components of Social Analytics is the first step in helping to effectively utilize the data.  Identifying your niche audience can help you to cater to a specific category so that your chances of success are guaranteed. It is therefore important to choose a solution that provides quick results for businesses to track social media behaviors in real-time and get immediate feedback on what will work for the product. It must also

1.     Provide trending views and drill-down capabilities
2.     Offer insights to make faster, smarter operating decisions across huge amounts of social data.
3.     Allow acquisition to revenue.
4.     Get faster insights into the key influences on your K-Factor and viral campaigns
5.     Understand what keeps customers engaged, and uncover the levers that can most impact revenues.

Social analytics can improve your business as it bring many insights along with a  host of benefits that include identifying new markets, understanding the competition and capitalizing on it. With social analytics you can identify product development opportunities and develop effective brand management, while also ensuring marketing campaign measurement and tracking.

Going beyond just listening to online conversations, true social media analytics provides valuable, actionable insight for shifting strategic focus.

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Compelling Industrial Engineering Services for Increased Business Value

Engineering departments of enterprises in majority of industries, like aerospace, automotive mobile communications and industrial equipments are subjected to a growing pressure to design, launch and manufacture new products in a short span of time. As Aerospace engineering services involve precision based development processes to make certain quality products have swift delivery rates, Organizations all over the world have to speed up their engineering capacities to keep up with the ever-increasing consumer demand. Enterprises that are capable of combining outsourced engineering services along with their own internal capacities are the ones that are profitable.


With the tremendous growth in the aviation industry, there are considerable matters in the aerospace engineering businesses that have to be addressed. This includes the incorporation of flexible processes that can deliver pioneering and high quality solutions to meet the global demands.  The consultants providing global engineering services have the experience and knowledge to implement best practices with outstanding and supportive coordination capabilities. Efficient engineering services generally comprise of the following domains


* Industrial Machinery

* Farm and Construction Machinery

* Electrical Equipments

* FMCG (fast moving consumer goods)


These services also support the Industrial and the FMCG services segments. These segments are ideally catered highly skilled domain expertise from offshore locations backed with local coordinators positioned globally through our near-site offices. Keeping in mind the challenges to this industry, these industrial engineering services offer the best value proposition ranging from cost excellence programs to reduced new product development time extended to prototyping and testing activities. Compelling industrial engineering services increase business value as there is


* Reduced engineering spend with increased productivity

* Drive cost excellence initiatives for customers

* Localization through global support

* Design to industrial products manufacturing capability and capacity


Over time many companies have comprehended that getting engaged with the right Engineering Services Outsourcing Company, there is greater value in helping them maintain and upgrade their cost structures. Offshore engineering service consultants can help in reducing the business costs and augmenting profits through automated processes that are standardized and integrated as they have the expertise to deliver best solutions. Offshore consultants deliver top grade, robust and highly efficient oil and gas engineering and also provide real-time assistance in addressing all issues successfully.


By choosing the best industrial engineering services a company can gain significantly from their methodical approach,  management of resources economical costs, and enhancement of  profitability that ultimately increases the business value of your organization.


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Challenges Faced By the Power Generation Engineering Industry

Climatic change concerns along with certain issues with Government Energy Policy round the globe is said to have posed serious challenges for the power generation engineering sector. For instance, in UK such challenges comprises of attaining 60 percent reduction in carbon dioxide by 2050, at the same time ensuring energy supply security that is reasonably priced within a competitive market structure. This means that the power generation engineering segment must pool in all their efforts to come up with innovative ways to cater to industrial clients. Furthermore, there are other challenges in developing innovative technologies that are offered on time and are technically efficient, thereby transferring the threat associated with the requirement to minimize emissions. Such challenges have resulted in the upsurge in R&D activities.

Power Generation Engineering Challenges

Some of the crucial challenges faced by the Power Generation Engineering sector are as follows:-

  • To be able to manage customer expectations in the market effectively

  • To ensure that there is continuous supply of energy even when there are natural disasters, industrial risks and other challenges

  • To be able to meet the regulatory challenges of safety, environment and health

  • Fluctuating supply and associated market prices

  • Scarcity of resources

Cost is an essential factor that needs to be addressed. However, power generation engineering companies are aiming to leverage from the engineering services outsourcing companies for process and product innovation, flexible technical capacity, attaining a strong hold on the local market, to experience advanced power generation solutions, and catering to the emerging offset demands. Owing to this need several companies have assessed their present manufacturing and engineering supply chain.

It is estimated that the global economy would expand four-fold by 2050 and it might even be experienced in the Indian subcontinent as well. This ensures massive improvements and economic benefits in the living standard and involves more utilization of energy. This led to the growing pressure globally to preserve the conventional energy sources that comprise thermal and hydroelectric energy, fossil fuels and many others.

Eminent companies specializing in engineering outsourcing services puts together manufacturing and power generation engineering services that enable their clients to fulfill the ever increasing demands in the power generation sector. They help their clients to minimize the time to market, enhance product performance, maximize capacity and revenue generation and finally minimize the product development cost.

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Efficient Data Center Solutions to Meet Your Requirements Successfully

Data centers are convoluted environments with numerous related systems.  Many data centers have evolved over the years, more so as IT organizations have worked to provide unique business advantages.  In order to successfully meet an organization’s requirements, an efficient data center must be meticulously planned, and executed to lessen disruptions while still responding to changes in business drivers. Although most data centers provide independent and reliable power, through diesel generators, and have battery backup systems, it is essential to select a data center that successfully protects  company’s data. The right data center is crucial for ensuring business continuity and the decision should be made based on the thorough assessment of the data center offering and its ability to answer your business’ needs in terms of cost, reliability, and security.


It is important to understand the type of IT environment a company has to their infrastructure and applications. To ensure that the client’s data and applications are safeguarded and protected at all times, many service providers invest a lot in putting up an extremely good infrastructure with fire suppression facilities, precision air-conditioning to maintain constant temperature, and power back-up systems. Every business is looking to grow and it is always a good idea to look at the scalability of a potential data center. A good data center solution will have provisions to make sure that your server has sufficient rack space and is completely dedicated to meeting comprehensive, long-term business needs and provide flexible and expandable data center space as needed.


Meeting your product-level, cabinet and rack assembly needs, an efficient data centre solution must successfully meet your other requirements by integrating hardware, software and peripherals. The solution must ensure building security and also offer quality security guards. It can meet your standard of requirement and use highly sophisticated security technologies like digital videos, electronic access controls, fingerprint recognitions, and retinal scans, to name a few. So opt for a data center that provides network neutral access to major telecommunications carriers and Internet backbones. Ensure that the data center chosen has complete uptime and that clients have constant reliable access to their data at all times. And efficient data center solution will always support quality and the solutions warranties must reflect the confidence and must test and warranty all the equipment and be focused on delivering superior service at all times.


The solution chosen must have best-of-breed industry standard components, and must also allow future growth and easy upgrades with regard to server, storage, and (HPC) high performance computing clusters. When combined with extensive hardware and software integration services and successful solution will be able to reduce both cost and risk.


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The Essentials You Need to Know about Travel Expenses in Itemized Tax Form 2,106

Most miscellaneous tax deductions can usually save you quite a bit of money, if you qualify. In many occasions, when you are unsure about the expenses that count as allowable tax deductions, they can also cause problems. A standard deduction can at times, get you the best possible refund, but if you are eligible, don’t miss out on larger refunds using itemized deductions.

Travel Expenses

Most of the travel expenses are regular and essential expenses of traveling when away from home for business. Personal expenses or expenses that are profligate and extravagant, travel expenses paid in connection with an indefinite work assignment cannot be deducted. What can actually be enjoyed as a deduction are those travel expenses incurred in connection with a temporary work assignment away from Tax home. Any work assignment in excess of one year is considered indefinite. Also, travel expenses are not deductable at a work location if it is realistically expected that you will work there for more than one year, whether or not you actually work there that long. If you realistically expect to work at a temporary location for less than one year, and the expectation changes so that at some point you realistically expect to work there for more than one year, travel expenses become nondeductible when your expectation changes.

A Quick glance at the deductible travel expenses while away from home:

1.     Travel by airplane, train, bus, or car between your home and your business destination. If you are provided with a ticket or you are riding free as a result of a frequent traveler.
2.     Using your car while at your business destination
3.     Fares for taxis or other types of transportation between the airport or train station and your hotel, the hotel and the work location, and from one customer to another, or from one place of business to another
4.     Meals and lodging
5.     Tips you pay for services related to any of these expenses.
6.     Dry cleaning and laundry.
7.     Business calls while on your business trip. This includes business communications by fax machine or other communication devices.
8.     Other similar ordinary and necessary expenses related to your business travel.

Most people find handling taxes and filings overwhelming. You will probably spend less on the help than you would on interest and penalties if things go awry. Taking the  help of a professional will give you the necessary support and guidance in all your tax issues be it a US India tax or itemized tax 2106.

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Ideal Data Center Solutions for OEM Appliances

Manufacturing OEM appliances is a highly responsible job. You have to build customized software applications that suit the needs of each customer. You also need to ensure that the quality standards are not compromised with. The appliances have to deliver reliable and optimum performances. The OEM appliances that you build should provide high speed accessibility to information without increasing the risks and costs, and with capabilities to accommodate the changing demands.


In order to ensure that all your processes are optimized you need data center solutions that will help address the issues competently and alleviate your concerns. The increase in applications and data can create severe storage server issues and derail your OEM processes. You have to have an impeccable inventory management process which helps in tracking the inventory in real-time and ensures that there are no outdated stocks that could lead to adverse effects on cost.


With the data center solutions there is greater integration which helps in making improvements easily and optimizing the processes effectively. Racks are provided for industrial applications, networks, web and data servers. Thus the solutions can be ideally used in any kind of environment. The solutions provide you with an integrated high performance computing cluster architecture that is simple to deploy and use with easy upgrading capabilities and facilities to accommodate for growth in the future without increasing the costs and risks. The data center solutions ensure that all OEM appliances are checked and tested before the final delivery.


The data center solutions facilitate you with competent unified storage solutions by providing a universal platform for allocation, consolidation and management of data storage enabling effective storage utilization and reduced administration. The solution is flexible and facilitates instant data sharing and data protection. It deploys a heterogeneous environment for storage that helps in fulfilling your goals in a cost-effective manner. It also assists you with rack-optimized servers and energy-efficient architecture and makes it suitable for virtualization, clustering and cloud computing.


The solution provides you with optimized processes for server consolidation and execution of critical data center applications. The unified storage solution provides you with a multi-purpose server that ensures maintenance-free storage. It provides you with excellent and simple data backup and recovery solutions that helps reduce costs with enhanced protection. You can deliver optimum performances with the unified storage solution and enjoy improved returns. The data center solutions provide you with innovative and constructive solutions for computing and storage purposes.

Fight against Counterfeits with Online Brand Protection Software

For any business, creating a brand name is as important as their business. It is an identity that helps to distinguish their products and services from that of their competitors. Without a unique brand name, it is difficult for companies to create a distinctive identity of their own, which in turn helps people to distinguish them from their competitors. The advent of the internet has helped enterprises and organizations immensely in establishing their brand names in the minds of the people. It provided a fertile venue for them to establish themselves, market their products and services and in growing and expanding their market. The different venues such as search engines, eCommerce, social networking, auction sites, emails, blogs, and microblogs provided companies ample opportunities to establishing a rapport with their target audience and thereby increase their market share of customers.

However, just like everything else, the internet also has its pros and cons. Its core values of anonymity, openness and global reach have been put to good use by the scamsters. If on one hand the internet has helped enterprises to increase their sales, on the other hand it also has thrown open a slew of opportunities for fraudsters to sell illegal product. Moreover, the lack of formal policing of the internet and the ease with which the value of brands can be hijacked online have resulted in the rise of counterfeit / gray market sales in unprecedented volumes. The different methods employed by the fraudsters for online brand counterfeiting are piracy, phishing, cybersquatting, malware, domain kiting, search engine manipulation, traffic diversion, false association, pay per click scams, framing, parody sites, negative newsgroup postings, counterfeit, gripe sites, and others.

Brand abuse leads to loss of reputation, trust, and revenue, which are enough to sabotage the future of any company. Hence, the best way to counter the moves of illegal sellers is to invest in online brand protection software that helps enterprises to identify the products that are being sold illegally, in what quantities, and at what price; on which sites the products are being sold; who is selling them; and how to shut them down. Such a move protects not just the brand name but also customer loyalty, web traffic, investment, revenue, and reputation.

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A Commanding Team for Addressing All Spear phishing Attacks with Proficiency

Phishing is a regular online activity where fraudsters send you fake email links or attachments. Once you click on this link or open the attachment all confidential information regarding your passwords and usernames are downloaded onto the cheaters’ database. Most of you may not consider this as a grave concern but with the sophisticated phishing methods and tools unwanted people can access your financial information such as credit card details, bank account numbers etc. As a result they can easily hack your accounts, rob you and leave you in a dire condition.

Phishing attacks have become more intense with the attackers targeting the bank customers and those associated with financial institutions and recently with the members of social networking sites. This is called enterprise spear phishing. They send you emails that seem as if they have been sent by your legitimate banks and financial institutions requesting for your personal details. It is easy to get cheated as the fake website resembles the original one and before you realize your mistake you have already shared your confidential information with strangers. In phishing the mode of operation is to target the people rather than technology as they are aware that there are robust security solutions to protect technology.

In a majority of the cases enterprise spear phishing achieves success as the people in the business are not aware how phishing works and what are the repercussions. Your organization may also have employees who are not adequately trained to recognize and handle such phishing attacks, and this can lead to unimaginable damages. It is better and economical to set up a plan that trains your employees prior to any phishing attacks in reality rather than investing heavily on employing remediation measures after the attack.

You require strong anti-phishing solutions to minimize the phishing fall rate and fail rate. The phishing fall rate is the percentage of users that falls for the phishing attacks and visits the fake websites. The phishing fail rate is the percentage that fails to identify the attack, visits the fake websites and reveals sensitive information. The people who work in your organization need to be trained and updated regularly so that the fall rate and fail rate can be reduced and the threats to your organizations be effectively lowered.

The anti-phishing solutions launch a mock phishing attack on your employees and study their responses. These solutions provide training to your employees on how to identify the attacks and deal with them appropriately. The responses of your employees are tracked and an action plan is created to educate them on how to avoid being victims of phishing attacks. The anti-phishing solutions make your employees more responsible and accountable by sharing practical tips on protection against phishing.

 

Get Online Brand Protection with Effective Solutions

With the tremendous growth in eCommerce, fraud protection for companies has become an increasingly vital issue as anyone with basic computer skills can develop and open an online marketplace to sell illegal products. Counterfeit operations are smooth and well- arranged, making it difficult for the actual businesses to save their hard earned reputation or impose stringent actions to stop these fake companies. Industries world-wide have suffered huge losses to counterfeiters.

While the advancement in technology has provided legitimate businesses the opportunity to sell products globally, it has also given counterfeiters, a cheap, simple, efficient method to go to market. Despite the fact that new threats to online brand identity surface on a regular basis, many businesses don’t have a comprehensive strategy in place yet to deal with them.

Considering the billions of dollars that companies spend to promote their brands and the costs and potential long-term effects of not taking action, it is vitally important to understand and address this problem. Businesses as well as enforcement agencies are getting aware of the need to implement effective measures that produce convincing and compelling results. They need to ensure that their brand names are adequately protected and to implement anti-counterfeiting policies to deal with this menace. These services can be employed to protect and authenticate genuine products.

ONLINE BRAND PROTECTION solutions that deliver competent and convincing results help many businesses to survive the onslaught. They also can help identify the products that are being sold illegally. They have been created to deploy intelligent practices to effectively identify the violators, assess the level of risks they pose, monitor their online activities continuously, provide prompt and real-time reports and execute stringent law enforcements. These solution providers also have extensive network of investigative and enforcement partners who can combat brand counterfeiting and can do the shutdowns for you.

It is therefore important for businesses to invest some time in careful and precise evaluations that will help you to implement the best strategies and solutions for a secured business future. It is vital to get proactive on developing a solid online brand protection strategy that will safeguard marketing investments, revenues, and most importantly, customer trust. Choose an online brand protection solution that has the ability to provide detailed information at the product, seller, and individual listing levels and allows your company to make informed decisions on where to spend your brand protection dollars most effectively.

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